FRAGMIN Resource Center
Eisai offers resources to assist you and your staff in the education and administration of FRAGMIN.Learn more >
FRAGMIN Self-Injection Demo Video
This Self-Injection Demo Video walks patients through the steps of injecting with a fixed-dose or graduated syringe.Learn more >
FRAGMIN Patient Education and Administration Kits
Educational materials, including an easy-to-understand reference chart, a step-by-step product brochure, and a how-to demonstration video, introduce patients to the use of FRAGMIN at home.Learn more >
Significant 45% total DVT relative risk reduction in hip replacement surgery patients
The NAFT* trial showed FRAGMIN was more effective than warfarin in early post-op dosing1
Primary endpoint was total DVT detection using contrast venography, performed 5.7 days (mean) after surgery. Secondary endpoint was incidence of proximal DVT.
Trial was multicentered (29 centers in the US and Canada) and double-blind. Patients randomized to preoperative FRAGMIN—initial injection 2 hours before surgery, and a second dose at least 4 hours postoperatively. Patients randomized to postoperative FRAGMIN—placebo injection immediately before surgery, and active injection at least
4 hours postoperatively. Patients randomized to postoperative warfarin—initial dose on the evening of surgery day.
In the North American FRAGMIN Trial (NAFT), 1472 patients undergoing elective hip arthroplasties were randomized to receive either FRAGMIN or warfarin.